CHEM& 261 Organic Chemistry I • 6 Cr.
Department
Division
The first of a three-course series in organic chemistry. The 261/262/263 series covers structure, nomenclature, reactions, and synthesis of organic compounds. Format includes laboratory work. Prerequisite: CHEM& 161 and CHEM& 162 and CHEM& 163.
Outcomes:
After completing this class, students should be able to:
- Introduction to carbon compounds and review of bonding theories
- Construct Lewis structures for organic molecules and ions, including applicable resonance structure and formal charge.
- Describe atomic molecular, and hybrid orbitals and how these relate to molecular shape.
- Use VESPR theory to predict bond angles, bond lengths, and polarity.
- Representative Organic Compounds and Functional Groups
- Describe the properties of carbon-carbon single, double, and triple bonds, including aromatic systems.
- Identify functional groups.
- Acid base theory
- Relate structure and acid base strength.
- Predict acid base behavior based on pKa, protoc/aprotic solvents, etc.
- Chemistry and properties of alkanes
- Apply the IUPAC rules for naming alanes, alkyl halides, and alcohols.
- Generate isomers and recognize different types of isomerism.
- Explain properties of cyclic alkanes and use cyclic terminologyI
- Introduction to IR spectroscopy
- Use and describe the EM spectrum and how it relates to energy.
- Describe the basic concepts associated with IR spectroscopy.
- Identify major functional groups on the basis of IR spectra.Explain the proper sample prep needed for IR analysis.
- Stereochemistry
- Identify, name, separate, and determine total number of isomers for chiral compounds (including meso).
- Nucleophilic Substitution and Elimination
- Describe the chemical and physical properties of alkyl halides
- Classify and rate reactions as Sn1, Sn2, E1, and E2 on the basis of substrate, solvent, nucleophile, and leaving group
- Give detailed mechanisms for Sn1, Sn2, E1, and E2 mechanism and understand their applications in terms of chirality and yield.
- Radical Reactions
- Write general radical mechanisms.
- Describe differences between the halogens for radical reactions.
- Describe differences between the halogens for radical reactions.
- Use radical terminology and explain thermodynamics of radicals.
